Table 1 Conditional probabilities of genotype given parental mating types and offspring disease status
| Parental mating type | Case genotype | Count | Probability of trio | Conditional probability |
|---|---|---|---|---|
| 1) MM × MM | MM | n 12 | p4ψ2/T | 1 |
| 2) MM × NM | MM | n 22 | 2p3q(ψ1 + ψ2)/T | ψ2/(ψ1 + ψ2) |
| NM | n 21 | ψ1/(ψ1 + ψ2) | ||
| 3) MM × NN | NM | n 31 | 2p2q2ψ1/T | 1 |
| 4) NM × NM | MM | n 42 | 2p2q2(ψ2 + 2ψ1 + 1)/T | ψ2/(ψ2 + 2ψ1 + 1) |
| NM | n 41 | 2ψ1/(ψ2 + 2ψ1 + 1) | ||
| NN | n 40 | 1/(ψ2 + 2ψ1 + 1) | ||
| 5) NM × NN | NM | n 51 | 2pq3(ψ1 + 1)/T | ψ1/(ψ1 + 1) |
| NN | n 50 | 1/(ψ1 + 1) | ||
| 6) NN × NN | NN | n 60 | q41/T | 1 |