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Table 1 Settings for creation of synthetic pathways

From: A multistep approach to single nucleotide polymorphism–set analysis: an evaluation of power and type I error of gene-based tests of association after pathway-based association tests

Number of genes 5 10 Total
Percent Causal 20 40 60 100 20 40 60 100
Number of pathways 15 11 10 5 15 11 10 5 82
  1. Genes were randomly sampled without replacement and placed into sets of genes, or pathways, of varying sizes. The percent of genes in the pathway containing at least 1 causal variant also varied across sets