Abstracts from the 25th European Society for Animal Cell Technology Meeting: Cell Technologies for Innovative Therapies

Table 1 (abstract P-318). Molecular characteristics of the nano-stars used in this study (sorted in ascending order of arm grafting density)

Designation	Name^a	Grafting density (arms/nm²)	Mn Polymer/Particle (kg/mol)	PDI	Subgroup^b
P300_5	NP@(PDMAEMA₃₀₀)₅	0.006	235	1.2	I
P242_9	NP@(PDMAEMA₂₄₂)₉	0.011	342	1.2	I
P528_20	NP@(PDMAEMA₅₂₈)₂₀	0.024	1660	1.3	I
P1100-4350_98	NP@(PDMAEMA₁₁₀₀-b-PDEGMA₄₃₅₀)₉₈	0.038	975000	1.6	n.a.
P1037_46	NP@(PDMAEMA₁₀₃₇)₄₆	0.054	7498	1.6	II
P1470_54	NP@(PDMAEMA₁₄₇₀)₅₄	0.064	12470	1.4	II
P312_337	NP@(PDMAEMA₃₁₂)₃₃₇	0.149	16513	1.4	III
P477_411	NP@(PDMAEMA₄₇₇)₄₁₁	0.182	30825	1.5	III
P1240_653	NP@(PDMAEMA₁₂₄₀)₆₅₃	0.289	127335	1.5	III
P439_657	NP@(PDMAEMA₄₃₉)₆₅₇	0.291	45333	1.4	III
P1616_679	NP@(PDMAEMA₁₆₁₆)₆₇₉	0.300	172466	1.3	III

PDMAEMA: poly(dimethylaminoethyl methacrylate). PDEGMA: poly(diethylene glycol) methyl ether methacrylate). PDI: polydispersity index (Mw/Mn). a: NP@(PDMAEMA_{Block length})_{Arm number}. b: The classification of the variants in the subgroups is based on the arm density and on the hydrodynamic radii (R_h) of the corresponding polyplexes covering a wide range of N/P-ratios and analyzed for size by DLS after a 30 min incubation (I: low arm density, 300 < R_h (nm) ≤ 1000; II: middle arm density, 50 < R_h (nm) ≤ 200; III: high arm density, 50 < R_h (nm) ≤ 300). n.a.: not available

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